Alex Chubykin, Ph.D. Post-Doctoral Fellow e-mail tel: 617-324-7006 Personal webpage

Research Interests

Persistent activity, reported in different cortical regions, may serve as a potential neuronal basis of working memory. This activity is usually induced in response to a sensory stimulus, and persists for up to several seconds after the stimulus is removed. Elucidation of the mechanisms involved is my main scientific interest.

Education

2000-2006:   Ph.D., Program in Neuroscience, Division of Cell and Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA

1998-2000:   M.S., Applied Physics and Mathematics,   Department of Molecular and Biological Physics, Moscow Institute of Physics and Technology, Moscow, Russia

1994-1998:   B.S., Applied Physics and Mathematics, Department of Molecular and Biological Physics, Moscow Institute of Physics and Technology, Moscow, Russia

Publications

Chubykin AA*, Atasoy D*, Etherton MR, Brose N, Kavalali ET, Gibson JR, Südhof TC.
Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2. Neuron. 2007 Jun 21;54(6):919-31. * - Equal contribution.

Boucard AA, Chubykin AA, Comoletti D, Taylor P, Südhof TC. A Splice Code for Trans-Synaptic Cell Adhesion Mediated by Binding of Neuroligin 1 to α- and β-Neurexins. Neuron. 2005 Oct 20;48(2):229-236

Chubykin AA, Liu X, Comoletti D, Tsigelny I, Taylor P, Südhof TC. Dissection of Synapse Induction by Neuroligins: Effect of a Neuroligin Mutation Associated with Autism. J. Biol. Chem. 2005 Jun 10;280(23):22365-74. Epub 2005 Mar 29.

Sara Y, Biederer T, Atasoy D, Chubykin A, Mozhayeva MG, Südhof TC, Kavalali ET. Selective capability of SynCAM and neuroligin for functional synapse assembly. J Neurosci. 2005 Jan 5;25(1):260-70.

Comoletti D, Flynn R, Jennings LL, Chubykin A, Matsumura T, Hasegawa H, Südhof TC, Taylor P. Characterization of the interaction of a recombinant soluble neuroligin-1 with neurexin-1-beta. J. Biol. Chem. 2003 Dec 12;278(50):50497-505. Epub 2003 Sep 30.